Lidocaine Patch 700mg Street Value
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The lidocaine patch is contraindicated in patients with known allergy to lidocaine, lidocaine, or its components (e.g. esterdermally applied or esterdiols).
A double-blind, placebo-controlled, randomized, crossover study of 7 days treatment in 51 patients with non-radicular low back pain showed that LIDODERM was superior to placebo for pain relief and was equally well tolerated. Similarly, a 12-week study of 51 patients with non-radicular low back pain showed that LIDODERM was more effective than placebo for pain relief and was equally well tolerated. Furthermore, the results of a double-blind, randomized, placebo-controlled study of 2 weeks treatment in 78 patients with chronic, non-radicular neck pain demonstrated that LIDODERM was more effective than placebo for pain relief and was well tolerated. More adverse reactions occurred in the placebo group than the active treatment group. The results of these studies support the recommendation that LIDODERM be considered in the treatment of chronic non-radicular pain. The lidocaine patch may also benefit the treatment of chronic cancer pain associated with nerve compression from bone metastases. Studies are underway to assess the effectiveness of lidocaine patches for the treatment of post-traumatic neuralgia and other neuropathic pain types.
The lidocaine patch was generally well tolerated in clinical trials of short duration, with a low incidence of adverse events. The most commonly reported adverse events were application site reactions (e.g. erythema, pruritus, and pain) and application site dermatitis. The most common systemic adverse events were dizziness (approximately 5%) and headache (approximately 5%). Adverse events were generally mild or moderate in intensity. LIDODERM was relatively well tolerated in long-term treatment trials in patients with painful diabetic peripheral neuropathy (21 days treatment).
Mechanism of action This medication works by blocking the transmission of pain messages along the nerves by blocking pain-carrying nerve impulses. Lidocaine, a local anesthetic, blocks the conduction of nerve impulses along the nerves by binding to nerve cell membranes and interfering with the normal flow of sodium, potassium, and calcium ions through the membrane.
In placebo-controlled trials, the lidocaine patches have been shown to have small but significant effects on improving pain and quality of life for people with postherpetic neuralgia (PHN). Note: Similar medications are available as over-the-counter medications (e.g. topical lidocaine creams and ointments), but these medications are much weaker and not approved for PHN. Lidocaine patches are also available without a prescription, but these weaker patch products are not recommended for pain control. In the case of pain control, the prescription-strength products should be considered the standard of care.
Key Facts The lidocaine patch 5% is an expensive, safe, and modestly effective topical analgesic for post-herpetic neuralgia. It has not been proven to be effective for other pain syndromes, and clinicians should strongly consider reports of its efficacy to be related to placebo mechanisms. 827ec27edc